We have formulated the following objectives:
- To provide a quantitative description of protein complexes, interactomes and networks in the mammalian glutamatergic synapse.
- To generate quantitative dynamic models, describing the main functional features of the synaptic networks.
- To reiterate on modeling by relating model predictions to synaptic function.
- To identify vulnerabilities in gene networks that are at the basis of human brain disease and may help design future therapy.